Of rectum cancer change cure

Cure is one of methods of important and auxiliary treatment of knot rectum cancer, also be a indispensable main component in writtening guarantee rectum cancer is treated integratedly. Remedial purpose is prevent and reduce recrudesce and move, heighten the long-dated curative effect that the operation treats thereby.

Cure is one of methods of important and auxiliary treatment of knot rectum cancer, also be a indispensable main component in writtening guarantee rectum cancer is treated integratedly. Remedial purpose is prevent and reduce recrudesce and move, heighten the long-dated curative effect that the operation treats thereby.

(One) assist the fundamental that changes cure

There can be concealment surviving tumor in the loop cell and local, far place or both all microscope leaves cancer cell kitchen range. When bump tiny with the cell kinetic appropriate when treatment is the most effective, decrease in tumour bear namely or grow when exponential percentage is larger, change curative effect fruit to be developed more easily. Have the preparation that already proved pair of this tumour are effective. Cellular poison cure shows a dosage- - reaction concerns, because this must give the biggest be able to bear or endure get dose, and period of treatment must be in order to exterminate in the limit of of all tumour cell.

(2) those who change cure is main get used to disease

Cure is changed after applying to art of patient of DukesB, C period.

Local change cure.

Terminal patient appeasement changes cure.

(3) the no-no disease that dies cure

Patient of evil fluid qualitative condition.

Patient of disease of serious heart and vessels or kidney function obstacle person.

Blood picture is not applicable the person that change cure.

(4) the way that changes cure

Systemic vein changes cure with medicine.

Liver artery spile changes cure: Move of liver of knot rectum cancer can be caused undertake sexual liver is destroyed, cause patient death finally. The liver of knot rectum cancer that did not receive treatment transfers a patient, in live period for 2.5 months ～ 6 months. A lot of medicaments are like 5-Fu and nucleotide of to oxigenate of pyrimidine of 5-Fu-DR(fluorine Niao) inside liver metabolization makes low poisonous product, via liver artery perfusion consequently chroma of this kind of medicaments increases, systemic noxiousness is reduced, and what liver artery spile changes cure is businesslike 50 ％ above, greatly prep above 5 - the curative effect that Fu vein gives drug () of about 20 ％ . This is through liver artery application changes cure to medication the mechanism of liver move cancer.

Canal of portal vein buy changes cure, small intestine of the classics in art fastens velar vein or the gastric retinal vein of transverse colon vein or apart pylorus 5cm inserts conduit, the time much arrangement of portal vein perfusion is in 6 hours after anastomosis of the bowel that finish, 5 - dissolve of 5000u of Fu600mg/m2+ heparin natrium in 5 ％ dextrose fluid, portal vein is successive perfusion 24h, drop fast for 40m1 ／ H, successive perfusion 7 days.

Antrum of auxiliary sex bowel changes cure in art: The perfusion inside alvine antrum changes cure medicaments, reduce one of measure that be identical mouth has a relapse, operation of tumour of the bowel that it is anus does not have the main component of tumour technology. Its method is: Bowel excises preparation first when the operation paragraph two end are apart from tumour to be in annulus of the belt that use cloth to plunge into alvine canal along 8 ～ 10cm each. Be like rectum cancerous criterion closedown is anal, next the infuse inside the alvine antrum to bump 5 - Fu30mg/kg(dissolve at the) in briny 500ml, after 30 minutes again ligation, cut off for should excising bowel paragraph activity arteries and veins, complete an operation by groovy measure.

Abdominal cavity changes cure: Make through drug giving directly inside abdominal cavity heighten of chroma of the medicaments inside abdominal cavity, hold time grows effect price. In the meantime, the medicaments concentration that forms to medical place inside this kind of abdominal cavity gives medical number hundredfold for vein, and system of medicaments classics portal vein is absorbed, the cancer cell inside system of vein of face each other and liver has better remedial effect. The commonly used medicaments that change cure cracks mildew element for silk of 5-Fu, MMC() , element of ADM(A mildew) , DDP(arranges chloric ammonia platinum) , Ling of Die of MTX(ammonia armour) etc. 5 - two medicine of Fu and MMC are operable have synergism. Can kill and wound cancer cell directly, it is clinical go up commonly used plan. Specific means is: The medicaments that change cure with 1. Liquid of 5L ～ 2L is attenuant, add lukewarm to 37 ℃ , the clip after celiac perfusion is in charge of 4 hours, make medicaments distributings equably inside abdominal cavity, contact all place and keep particular function time, use negative pressure to will turn cure juice as far as possible next epispastic, with reducing medicaments accumulate. General everyday 1, use consecutively is one period of treatment 5 days.

Arterial spile changes cure: Terminal rectum cancer cannot effect a radical cure all right art or short-term after appeasement sex tumour is excised inside occurrence recrudesce move, change cure to be able to be its cure to offer a better way via arterial spile. In the meantime, use arterial spile to turn cure medicaments toxicity response is small, reduced systemic noxiousness reaction, shortened remedial time, if be before art,application still can raise operation excision to lead.

(5) large intestine commonly used combination changes cancer cure plan

1. FIVB5 - Fu500mg ／ M2d1-5

DTIC150mg ／ M2d1d2

VCR1. 4mg ／ M2d1d8

BCNU60mg ／ M2d1

21 days are one cycle.

2.FAM5 - Fu600mg/m2d1d8d1-5

ADM30mg/m2d1d8

MMC10mg/m2d1

21 days are one cycle.

3.CFCPT10mg/m2d1-10

5-Fu500mg/m2d1-5

21 days are one cycle.