Mutation of ribonucleic acid of to oxigenate of line bead body can spur tumor move

Cancer often can spread in tumor deadly biff is started after other organization. One is published in " science " the process that the research on magazine network edition understands this to be called to transfer for people provided newest understanding.

　　 cancer often can spread in tumor deadly biff is started after other organization. One is published in " science " the process that the research on magazine network edition understands this to be called to transfer for people provided newest understanding. Researcher report says, ribonucleic acid of to oxigenate of line bead body (DNA) mutation can spur move, but this one process at the same time can by medicaments place changeover- - be on small rat body at least such.

Body of bead of 　 　 line is from a kind of when accede over there the mother tiny organelle, its action is equivalent to cellular power station. Line bead body has his DNA, the name is MtDNA. 10 years ago, cancer researcher notices, the MtDNA in tumor cell often can produce mutation- - its level greatly prep above is organized normally. This part results from MtDNA and was not surrounded by protein place, because this is easier,be injured. A few researcher are conjectural, mtDNA may cause cancer. But also somebody thinks, mutation is a by-product of cancer merely; They emphasize, those people that have disease of wired bead body do not have remarkable cancer trend, at the same time cancered risk is not come from at the mother, cannot affirm line bead body and cancer accordingly form about.

The part that 　 　 acts in cancer to study MtDNA is choppy, the Jun-IchiHayashi research group that Japan builds wave university and co-worker had the MtDNA in cell of tumour of two kinds of small rat trade- - a kind of cell can produce move and another kind criterion won't. Be opposite with cell of this kind of cross when researcher after small rat carries out hypodermic, these cells development is tumor and diffuse finally gradually lung. Compare with the small rat photograph that injected to come from the cellular MtDNA that shifts the liability lesser, the small rat that move cell MtDNA carries inside those body formed more lobar tumour, this means MtDNA is final culprit. However MtDNA is formed with original tumour it seems that have nothing to do- - after the MtDNA trade that diverts a cell oneself in the future when researcher arrives in normal cell, latter did not form tumor.

　 　 transfers cellular MtDNA to pass two kinds of mutation it seems that- - can cause line bead system oxygen of excessive production active, this is a kind of poisonous member that can injure DNA- - will complete their Babylon action. After researcher joins a kind of medicaments that recruits these members to the middle of the drinking water of small rat, these by hypodermic the small rat that transfers a cell did not form new tumour almost.

Researcher RobertTaylor points out the line bead body of university of Ka Sier of button of 　 　 England, this paper is " " of stunt of a technology, he points out at the same time, antioxidant can restrain the fact of move to bring a hope for prospective research. However, the KorneliaPolyak of institute of cancer of Dana-Farber of American Bostonian university emphasizes, the clinical test that treats cancer with antioxidant produced jumbly result, the patient that and let accepts chemotherapy uses antioxidant to treat the influence the effect.