Study discovery decides the albumen that whether can breast cancer diffuse

Recently, american scientist discovered one kind can decide whether breast cancer can diffuse reach the albumen that evolves into mortality cancer. Researcher expresses, because this kind of albumen is located in inside nucleolus, compare difficulty as medical target so and have potential risk.

　　 recently, american scientist discovered one kind can decide whether breast cancer can diffuse reach the albumen that evolves into mortality cancer. Researcher expresses, because this kind of albumen is located in inside nucleolus, compare difficulty as medical target so and have potential risk. Nevertheless this kind of albumen can help monitoring the dangerous sex before the patient understands breast cancer to diffuse, decide to adopt plan of which kinds of treatment thereby. Relevant paper will publish on March 13 " natural " (Nature) on the magazine.

The albumen name that this discovers 　 　 anew is SATB1, it can change the expressive standard of a variety of 1000 gene in breast cancer cell. Berkeley of university of California of one of research co-worker, United States divides the TerumiKohwi-Shigematsu of school to say: "All sorts of control that can promote breast cancer cell to inbreak to suffer SATB1 to the molecular method of new environment. "All sorts of control that can promote breast cancer cell to inbreak to suffer SATB1 to the molecular method of new environment..

Researcher studies 　 　 further discovery, SATB1 can transform the dimensional layout of DNA, change then surround in the albumen all round segment of group of a few gene, be started effectively in the process that packs " in this change " or shut a few gene.

　 　 researcher detected the SATB1 circumstance in the breast cancer cell of 1300 many example, the result discovered a striking pattern. It is namely in almost entire case, the SATB1 that the cell includes is more, the aggressive sex of breast cancer tumour is stronger.

　 　 next researcher had a test on small rat body. Should disturb a technology to move from inside cell of breast cancer of tall invasive small rat with RNA after dividing SATB1, the growth of tumor is restrained; And join SATB1 in providing cell of breast cancer of invasive small rat hind, these cells become similar move sex cell.

This one new protein that 　 　 discovers this will offer good forejudge test for breast cancer patient. The JoseRusso of center of cancer of Fox · Chase says Philadelphia of one of co-worker, United States: "If be in of the patient former first this one albumen discovers in tumor, the prognosis that we can understand this patient (Prognosis) will differ, cause the remedial program with different choice likely consequently. Cause the remedial program with different choice likely consequently..

The FrancesShannon of Australian state-maintaineding university expresses, "A large number of gene DNA" in cancer cell is discussing all the time before researcher pack the metabolic circumstance of " , but do not have a law to make clear the cause that causes these change. This research determined among them cause, forward more took one step. "Nevertheless, her complement says, next the problem is " it is the elevatory " that what caused SATB1 level.