Large intestine cancerous pathogeny

Cancer includes large intestine colonic cancer and rectum cancer, it is common malignant tumor. This disease with the male more see, of the men and women than making an appointment with 1.65 ∶ 1, come on the age is made an appointment with 75% in 31 ～ 60 years old, come on the height is controlled in 45 years old, but 30 years old of the following youths large intestine cancer is not scarce.

Cancer includes large intestine colonic cancer and rectum cancer, it is common malignant tumor. This disease with the male more see, of the men and women than making an appointment with 1.65 ∶ 1, come on the age is made an appointment with 75% in 31 ～ 60 years old, come on the height is controlled in 45 years old, but 30 years old of the following youths large intestine cancer is not scarce. This disease is in our country come on the characteristic is: Large intestine of cancer come on the age Bioumeiyao shifts to an earlier date 10 years, and youth large intestine Bioumeiduo sees cancer; Large intestine cancer is common fall at colon paragraph, domestic place sees make an appointment with close half the number to be located in rectum, the occurence rate that compares Euramerican rectum cancer is tall.

Cancerous pathogeny has not make clear large intestine, likelihood and following element concern:

(1) food element: Hair sick condition of cancer is in large intestine difference of different country, different area is very big, because of,thinking tall fat cookbook and food fiber are insufficient commonly is main hair cause of disease. Fast adipose food, contain the food of saturated fatty acid especially, after feeding, make intestinal cholic acid, cholesterol quantity increases, in bowel the action of path bacterium falls, this both metabolization child may be large intestine the material of cancer that cause disease. Food fiber (wait like cellulose, pectic, half fiber, lignin) the hangover inside can attenuant bowel, increase amount of excrement and urine, make dung is accelerated for nothing from alvine path platoon, reduce carcinogen and the chance that mucous membrane contacts large intestine, reason takes food contain a lot offibrous food to be able to reduce large intestine hair ill opportunity of cancer.

(2) colon is polypous: According to statistic, the person that cancerous incidence of a disease does not have colonic polyp in tower above of the person that have colonic polyp makes an appointment with large intestine 5 times. Colonic polyp basically is adenoma tubal account and tit shape adenoma (also call villiform adenoma) . Constituent pathology confirms, colonic adenoma but canceration, especially latter canceration rate can amount to 40% ～ 50% , familial sex sends disease of sexual colon polyp more, canceration occurence rate is higher.

(3) is chronic colitis disease: The large intestine of cankerous sex colonitis prep above of cancerous occurence rate is normal crowd 5 ～ 10 times, chronic bacterium sex is dysenteric, chronic amoeba bowel disease and clone disease produce large intestine cancer person contrast than be the same as the age the crowd is fast. According to thinking, in the process of inflammation hyperplasia, often can form phlogistic sex polyp, produce canceration then, but what need time longer, than the large intestine of colonic polyp cancerous occurence rate is low. After female reproduction fastens cancer to be treated via radiating, often cause radioactivity rectum colonitis, minority can produce canceration. Chronic schistosomiasis, because egg of alvine wall bug is deposit as exciting as toxin, the likelihood brings about alvine mucous membrane polyp of chronic ulcer, epithelial hyperplasia, phlogistic sex is formed, cause canceration then.

(4) other factor: Inferior saltpetre amine compound, the likelihood is large intestine one of elements of cancer that cause disease. Molybdenum is nitric acid the indispensable composition in reductive enzymatic action, when content of the molybdenum in soil decreases or be lacked, the nitric acid salt that can make a plant medium is accumulative, nitric acid salt is to form inferior the predecessor of saltpetre amine. The element causing disease that sends gender and disease of blemish of acquired character immunity to also can make this disease formerly.