Lung cancer is individual turn treatment

Be based on the cure of lung cancer standardization of evidence of abide card medicine, it is lung cancer a milepost on remedial history. And on the foundation that treats in standardization, the lung cancer that gene group learns knowledge to deepen and becomes especially according to existing knowledge is individual turn treatment, will be a thoroughly remould oneself on lung cancer cure more change.

Be based on the cure of lung cancer standardization of evidence of abide card medicine, it is lung cancer a milepost on remedial history. And on the foundation that treats in standardization, the lung cancer that gene group learns knowledge to deepen and becomes especially according to existing knowledge is individual turn treatment, will be a thoroughly remould oneself on lung cancer cure more change.

So called lung cancer is individual turn treatment, those who point to is to be patient of certain lung cancer to measure a body to spend the remedial strategy that creates place to make. current condition, a kind individual the lung cancer that change treats strategy, must count clinical factor, must count the factor that functional gene group learns and functional albumen group learns more.

Those who be based on clinical element is individual turn treatment

Lung cancer is a the mainest clinical and prognostic index in installment, treat strategy according to what make lung cancer in installment, it is current everybody is accepted individual turn treatment one of basic standards. Announce by 2005 " Chinese lung cancer is clinical diagnostic cure is how-to " with American cancer integrated network (NCCN) lung cancer is how-to, make a person say also is most most the part of elite, treat in installment namely the principle carries out detail with what treat in installment.

The lung cancer that is based on clinical element is individual turn treatment, although already took one stride compared with the cure of pure basis experience, but it still is not real significance those who go up is individual turn treatment. For example Ⅰ period lung cancer is a quite big group, the basis treats a principle to use identical operation to treat strategy to this one group in installment, the patient that still has 30 ％ of 20 ％ ～ lives cannot exceed 5 years, these patients accept actually not be individual turn treatment.

Those who be based on gene level is individual turn treatment

Human gene group plans to make we know, each each body is distinctive, the distinctive gene chart that depends on each each body having extraordinary (or it is expressive chart) . Accordingly, the lung cancer that is based on functional gene group to learn with albumen group is individual turn treatment, make us right likely act according to actual circumstances of patient of each lung cancer, the design goes out to be aimed at this one patient only distinctive, the remedial plan that has best effect and lowermost poisonous side effect so far.

Already had the anticarcinogen content choice that is based on tumor element characteristic at present, if according to EGFR mutation the circumstance chooses patient of appropriate lung cancer to undertake Yiruisha is treated, be expected to make lung cancer cure more individual change. Can be without ground of be concerned about to say, in last few years a large number of target the emerge in large numbers to medicaments, just about lung cancer is individual turn treatment clinical remedial prelude. In addition, be based on biology to indicate the plan changing cure of content chooses also is current heat.

Have trap everywhere, it is an outlet everywhere

Undoubtedly, the research that functional gene group learns makes a person dazzling as a result, whether do we have reason to believe, of cancer individual change remedial times to want advent immediately? Actually, the research of lab, clinical little sample book returns the wide gap with huge existence between result and clinical application, should span this one chasm is not easy thing, but can anticipate, make progress to the research of gene form function will advance rapidly.

One of main problems are individual the sample size that changes research of remedial element biology gets the limitation of all sorts of conditions, the sample size that studies at present all lesser, the result inference of will little sample book is used at clinical practice to make we take branch road likely. Want to enlarge sample size to animal farm to be hard to obtain at tumor organization again. In addition, at present relevant research also can be accomplished only as a result detect specific crowd is opposite some some kind the reaction of medicaments, still cannot specific to certain body, this also brings a lot of variable for clinical actual application.

It is specific technical issue next. The data mining of the tremendous biology information content that place of technology of for example chip brings and statistic are analysed, put in a lot of difficult problem, the technology is far still not perfect. From this, in clinical trial, terminal to clinical and main observation index, tremendous information content can become instead disturb for a kind, make the least bit of the analytic difference of twin problem likely, erroneous with a thousand li.

Accordingly, below current condition, unfavorable acquired preliminary acknowledge popularizes application easily to arrive in clinical practice. Such OK saying, of cancer individual turn treatment, have trap everywhere, it is an outlet everywhere, the key depends on the chasm between fill lab and clinical practice.