Saturday, September 13, 2008

The humoral immunity of cancer of the stomach

The humoral immunity of cancer of the stomach: The relationship of cancer of the stomach and humoral immunity is relatively close. B lymphocyte falls in antigen stimulation, change finally into antibody to produce a cell, it is young oar cell more, transfer model oar cell and typical oar cell, all have the function that synthesizes immune globulin, friend also says immune globulin produces a cell.

The humoral immunity of cancer of the stomach: The relationship of cancer of the stomach and humoral immunity is relatively close. B lymphocyte falls in antigen stimulation, change finally into antibody to produce a cell, it is young oar cell more, transfer model oar cell and typical oar cell, all have the function that synthesizes immune globulin, friend also says immune globulin produces a cell. Determine directly of cell of generation of the antibody in gastric organization more or less to reach its to distributing, the immunity that can understand airframe to rise to place of antigen of particularity of cancer of the stomach reacts. Cell of generation of IgG of normal stomach mucous membrane is occupied 31.6% , in organization of cancer of the stomach IgG place produces a cell to increase significantly, occupy 56% . And 3.5 times cell of generation of IgG of the mucous membrane other the cancer that is apart from 3cm of kitchen of cancer of the stomach is cancerous organization.

IgA has secrete model (SIgA) with serum model (IgA) two sort. Normal stomach mucous membrane produces a cell to give priority to with IgA, occupy 55.1% . SIgA is divide a combination with by two monomer and the exudation of geminate body IgA, distributing to form immune protective screen in surface of gastric bowel mucous membrane, the adsorption that prevents bacterium and virus restrains his to grow, prevent antigen sex material to enter mucous membrane. So the IgA in gastric bowel path is in order to secrete model the form of IgA exists. SIgA in gastric juice complete accepted PH condition restrict, in stability of content of PH5.0 above SIgA, although pepsin exists normally formerly, but because also be not had by activation,digest active. Home reports positive of cancer of the stomach leads 68.1%~87.0% .

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