Cancer patient is sending sexual tumour formerly (Primarytumor) was transferred or be after diffusing, can ask what still can do normally, but the result that often gets is to do not have what method.
Patient of cancer is sending sexual tumour formerly (Primarytumor) was transferred or be after diffusing, can ask what still can do normally, but the result that often gets is to do not have what method. Come from group of gene of cancer of lab of cold spring harbor research center (CancerGenomeResearchCenter) researcher achieved an important discovery: A kind of cell can the lung cancer of adjusting control diminutive, dormancy changes direction large, embezzlement sex diffuses- - these meetings bring about cancer disease to have death.
Achievement of this one research announces in " science " (Science) magazine, those who head this one research is Dr. VivekMittal of lab of cold spring harbor, the postdoctoral researcher that the first author of the article is its lab is become high surely (DingchengGao) .
Mittal expresses, "The malignant former tumor that send a gender is in for the most part clinical other organ " had diffused when diagnosing, "Current effort basically is in centrally prevent move to diffuse, but contradictory is, how does the tumour of concerned dormancy transfer other organ, become bigger, the mechanism of deadly sex, we understand rarely. We understand rarely..
cancer can happen in human body any organizations or organ. Say commonly, can diffuse and malignant tumor is transferred. We know, the happening of cancer just appears at the beginning a cancer cell, its dissension becomes two cancer cell, continue to break up go down to be able to produce one small round cancer cell and form tumor. When tumor development weighs 1 milligram about to syringe needle size, it already contained 1 million cancer cell; Arrive when marbles size, have 1 billion cancer cell about.
Gao expresses, "Our research basically is centered in small rat to send sexual tumour cell how to diffuse formerly, be in like lung small move environment is built on such the 2nd organ (Micrometastases) " , "We are analytic new student switch (Angiogenicswitch) crucial, and prove small move can help the EPCs in marrow (cell of the body before endodermis) adjusting control switch, activation blood-vessel is generated, the grand move that becomes the tumor change of dormancy condition minatory life (Macrometastases) . The grand move that becomes the tumor change of dormancy condition minatory life (Macrometastases) ..
Researcher is in when discovering tumor exists in experimental small rat, a kind of calls Id-1 albumen level in EPCs can increase substantially, disturb a technology through RNA, researcher block broke the expression of the Id-1 in live body animal, prevent EPCs flow direction to turn thereby shift dot, restrained new student switch thereby, the process that this disturbed small move Xiang Hong is transferred in small rat.
is important is, researcher used this kind of method to increase to carry the surviving rate of the animal of tumor, next researcher hope to be able to have similar research inside human body.
Mittal expresses, "This research put forward a new remedial drone, the alternative drone that also shows EPCs may be united in wedlock with the photograph that change cure, become cancer of a kind of cure to had changed the method of the patient of lung. Become cancer of a kind of cure to had changed the method of the patient of lung..
The research before " basically emphasizes target the cancer cell to transmissibility mutation, but have a few drawback so, fight a gender e.g. what cancer cell can produce pair of drug that change cure. We think the target stability to tumor small move element, for instance EPCs, future may become effective cancer treat a method. Future may become effective cancer treat a method..
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