Fight blood-vessel to generate remedial tumour

Go up century at the beginning of 70 time, fokeman teachs college of medicine of university of American haing Buddha to offer the tentative plan of tumor hunger therapeutics above all, form stage by stage later fight blood-vessel to create remedial concept. An expert appearance fights blood-vessel this kind to make curative thing is " cry in dozen call killed sea land cavitation cure fights in the world, it is one low-key, concealment, the armed working team of enemy's rear area of do with sb unconscious " .

The century on 　 　 at the beginning of 70 time, fokeman teachs college of medicine of university of American haing Buddha to offer the tentative plan of tumor hunger therapeutics above all, form stage by stage later fight blood-vessel to create remedial concept. An expert appearance fights blood-vessel this kind to make curative thing is “ cries in dozen call killed of great capacity land cavitation cure fights in the world, it is one low-key, concealment, the ” of armed working team of enemy's rear area of do with sb unconscious.

However, effect of medicaments research and development and progress are not good. Although testimony of small mouse experiment understands the United States,the hemal endodermis cell of development controls element swollen to cancer have narrow and restrain curative effect apparently, but this medicaments finishs Ⅱ period only in the United States clinical trial, interrupted 2005.

Outside the wall blossomming in the wall sweet. Go up century 90 time, with great concentration of a batch of our country young scientist that return from the United States tackle key problem, use “ protein answer sex ” this one technology, restrain hemal endodermis cell element to be changed into him our country fight blood-vessel to generate medicaments —— favour of a kind of new drug is spent. Fight blood-vessel to make remedy very small to the action of dormant blood-vessel inside human body, won't endanger normal organ commonly.

Is the clinical strategy that fights blood-vessel to make treatment effective? Tens of home hospitals entered the throughout the country clinical trial. May 2005, on annual meeting of association of American clinical tumour, sun Yan reported fight blood-vessel to generate medicaments favour to spend in our country clinical Ⅲ period test result: Came to shared 326 patients to accept 2004 2001 fight blood-vessel to make treatment, the patient tumor that has 35.4% is apparently contractible; 167 patients accept simplification cure, among them the tumour of 19.5% is apparently contractible, its difference has remarkable statistical sense.

According to newest statistic, at present at least more than 30 kinds of anticarcinogen thing that fight blood-vessel to make factor are undertaking in each country clinical or clinical early days experiments.

New method needs more proof

Although fight blood-vessel to generated cure to offer tumor to treat new approach, but this still is one kind is in developing new treatment, a lot of serious problems remain to explore. For instance, because come out time is still short, existing clinical data and experience are little, the limits of research and deepness are insufficient, potential long-term curative effect and side-effect still need observation.

In fighting blood-vessel to make treatment, fighting blood-vessel to generate is with what change cure to undertake in coordination, the problem in having a lot of clinical treatment was not solved. For instance, think to fight new unripe hemal treatment to be able to bring about tumor blood commonly for decreasing, tumor may appear lack oxygen condition, but how be opposite put cure, change cure to add quick? In fighting new unripe hemal treatment to change cure pattern jointly, how to decide optimal medicaments dosage is mixed medical time? Whether should give before changing cure fight blood-vessel to make remedy? The time dependence that fights blood-vessel to create curative effect is strong depend on at dosage, should does how long give drug? How long to treat? These need many clinical trial result to come test and verify.

Biology of hospital of Zhongshan university tumour treats central Professor Huang Wenlin to point out, fight new unripe hemal treatment to basically be aimed at the tumour with new student sensitive blood-vessel, wait like cancer of cancer of the liver, lung cancer, bowel, do not suit all tumour.

Fight the ceaseless get rid of the stale and bring forth the fresh of all sorts of viewpoints of tumor and genre, be based on whole tumour to treat the change of train of thought. Li Kai says, long-term since, clinical cure viewpoint all the time confine makes at striving for tumor tumour body narrows down to disappears, short-term effect became main target. But, from go up since century end, medical bound produced major change on the strategic thought that tumor treats, it is OK that the tumor change that is not about to accept control to grow becomes a kind pilot is chronic disease, strive for a patient to be able to take tumour to live to prolong life, improve life quality.