Saturday, January 26, 2008

The huge bite cell of patient of cancer of the stomach gobbles up functional bring down

Huge bite cell gobbles up a function: Gobble up and digest a function of huge bite cell to be able to reflect the immune condition of airframe on certain level. Have report health person 30, gobble up per cent for 54.25% , and patient of cancer of the stomach is 68 times 36.59% . The huge bite cell that makes clear patient of cancer of the stomach gobbles up a function apparent shrinkage.

Huge bite cell gobbles up a function: Gobble up and digest a function of huge bite cell to be able to reflect the immune condition of airframe on certain level. Have report health person 30, gobble up per cent for 54.25% , and patient of cancer of the stomach is 68 times 36.59% . The huge bite cell that makes clear patient of cancer of the stomach gobbles up a function apparent shrinkage. Of cancerous patient can make without cellular ooze fluid or serum the huge bite cell of normal person gobbles up ability to reduce, and malignant tumor patient, after the operation excises tumor, huge bite cell gobbles up what ability can have different rate to pick up. Patient of this clew cancer is likely its are humoral in existence restrains factor some kind to cause huge bite cell to gobble up ability to reduce. Hormone of huge bite action (Tuftsin) a kind of be milt generation natural sex gobbles up action to promote peptide, its structure is revive ammonia is acerbity - lysine - proline - ammonia of essence of life is acerbity, immunity is fought affect and fight tumor action. Huge bite cell can be carried present antigen, can secrete leucocyte but element - 1 (IL-1) wait for active material in order to adjust, the proliferous become divided that controls lymphocyte. Huge bite cell has the particularity that gobbles up action hormone to accept put oneself in another's position, tuftsin can be rapid of particularity be united in wedlock with huge bite cell, increase its active and the contact of its and T lymphocyte, raise huge bite to be opposite thereby of tumor cell kill and wound destroy effect, the cellular poisonous action of stimulative T lymphocyte, kill and wound tumor cell. Tuftsin raises nature to kill and wound a cell (NK cell) active, it is as exciting as the NK cell that all sorts of lienal effect cells produce factor and interferon about, but the possibility that also cannot eliminate its to stimulate NK cell directly. Animal experiment is normal blood of the week outside bandicoot the NK active close of lymphocyte and lienal cell, via leucocyte interpose element - after 2 stimulation, all can produce apparent LAK active, clew is normal inside the milt below the circumstance nonexistent control an element. The NK active of lienal cell and element of interpose of its dialogue cell - 2 exciting reactivity all have higher level; Compare with normal bandicoot photograph, outside bandicoot of cancer of the stomach all round blood the NK of lymphocyte and lienal cell, LAK is active all lower, it is with lienal cell especially very; Blood of the week outside comparing bandicoot of cancer of the stomach of lymphocyte and lienal cell kill and wound cellular active, no matter be NK or LAK cell active,can discover further, all with lienal cell apparently low, announce thereby lienal memory of bandicoot of cancer of the stomach is in certain control gene, the NK active that can restrain lienal cell apparently and element of interpose of its dialogue cell - the reactivity of 2. According to experiment and clinical research: Think to enter exhibition period cancer of the stomach can function of immunity of whole of disappear weak patient, among them milt place suffers an effect more apparent. Immunity of dissolubility of tumor cell excretive controls gene, and in tumor antigen stimulation falls, the immunity that activations inside lienal cell controls gene may be to bring about the prime factor with low function of immunity of milt of patient of progress period cancer of the stomach. These active that control gene return as tumor progress incline to heighten. Its action form is the before restraining a cell body that the course of study inside activation milt already existed on one hand; Still can weaken the NK inside body to wait directly on the other hand kill and wound cellular active, can affect biology reaction conditioning agent active to this kinds of cell buildup action.

Current, the cancerous antigen in thinking tumor patient circulates and the immunity that its and corresponding antibody form are compound content but with kill and wound a cell the FC of one suffers body to be united in wedlock, close then kill and wound a cell the noxiousness action to cancer cell. It is the immunity related tumor essentially complex matter. Call close factor (Blockingfactor) . The immunity of blood of week blood, lienal outside taking patient of exhibition period cancer of the stomach vein and lienal blood is compound the nonsignificant difference between content value, the result that making clear as complex as the immunity related tumor matter to lift is reaction of immunity of sex of a kind of whole body and be not splenetic of bureau be confined to special reaction, can think complex matter place brings about immunity thereby close action participates in what systemic immunity checks status to fashion a process not only, also weaken the integral immunity function that takes patient of exhibition period cancer of the stomach at the same time.

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