Large intestine cancer is replaced with Yi Li health the plan that change cure obtains significant progress

The clinical research that whether applicable Yi establishs cancerous patient to add up to fluorine Niao pyrimidine to change cure plan for Kang Lian obtained Chinese large intestine recently significant progress.

The clinical research that whether applicable Yi establishs cancerous patient to add up to fluorine Niao pyrimidine to change cure plan for Kang Lian obtained large intestine of 　 　 China recently significant progress. Xu Jianming of director of division of tumour of 307 hospitals enteron passes the liberation army clinical research discovered comfortable operable Yi Li is replaced health large intestine cancerous patient. This studies for the patient reasonable use Yi Li is replaced health the plan that change cure provided scientific basis.

It is current that Yi Li replaces calcium of Kang Heya folic acid clinical use two of cancer at treating terminal large intestine to basically change cure plan. However, because abroad reports Yi Li sends sexual diarrhoea occurence rate for Kang Chi taller, domestic clinician dare be not used more.

Be aimed at this one problem, the relation that to Chinese large intestine sex of much condition of cancerous patient and gene of healthy person UGT1A reachs they and Yi Li to replace health noxiousness undertook Xu Jianming analyse. He chooses 100 healthy volunteers and 70 large intestine cancerous patient regards research as the object, discover the Chinese is replaced with Yi Li health hind appearing deputy reaction odds is not big, tall without Hesperian. Consider to confirm, person of the Han nationality is replaced with Yi Li health the occurence rate of deputy reaction is 5% the left and right sides, the 20% diarrhoea occurence rate of the left and right sides that report under the west apparently. Xu Jianming discovers in research, distributing in Chinese crowd the UGT1A of more genotype correspondence is enzymatic all taller, this may bring about noxiousness reaction to be in the crowd occurence rate is inferior. The Chinese's mutation distributings of circumstance and Euramerican report different, this may be the Chinese replaces health diarrhoea occurence rate with Yi Li the main reason of apparent on the low side.

Xu Jianming reminds, before to large intestine carninomatosis person replaces health remedy with Yi Li, should detect above all patient UGT1A gene mutates, the possibility that if have variation,produces diarrhoea is larger, the doctor is about to had done corresponding auxiliary cure to prepare; If do not have mutation, the possibility that produces diarrhoea is very little.